Joe, a programmer and obsessive self-quantifier, and Emily, a budding comedy performer, are happily married until they decide to use one another in their work.

Three lives. Buffalo detective Lt. Cristofuoro, whose catatonic wife is in hospital, takes a special interest in Eric Komenko, a juvenile who killed his parents and will be freed on his 18th birthday. So has Lori Cranston, 15 or 16, her body fully developed and the object of lust by her boss and her mother's new boyfriend. She keeps a scrapbook about Eric, and when he's released from custody, she hides in the backseat of his car, insisting he take her with him on a trip toward Albany where he's planning to meet a girl. Cristofuoro is certain Eric will kill again, so he follows. It's clear early on that Cristofuoro's probably right, but what's Lori's motivation?

Johnny has just been released from prison, and gets a job in a cafe beside waitress Frankie. Frankie is a bit of a loner, but Johnny is determined their romance will blossom.

Laura's expecting. Her husband, Steven's a loving guy but has little time for her. Her mom lives thousands of miles away. Forced to give up on her dreams, she's always been a bit edgy. A C-section drives her over the edge, making her see things in a different light. A creepy babysitter doesn't make things any better. She begins seeing things, trusts no one, as she goes into self-destruct mode.